Invalid object name 'antibody_LocusMapping'. Anti-IL1B Antibody, Clone 1A7 - OriGene
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Anti-IL1B TRUEMAB Antibody Clone 1A7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA506440
  • IL1B mouse monoclonal antibody,clone 1A7
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400196) , 20ug Explanation
100ul 325 In Stock
CF506440
  • Carrier-free (BSA/glycerol-free) IL1B mouse monoclonal antibody,clone 1A7
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
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Also for IL1B (NM_000576)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human IL1B(NP_000567) produced in HEK293T cell.
Clone NameClone 1A7 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:4000,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens interleukin 1, beta (IL1B)
Alternative NameIL-1; IL1-BETA; IL1F2
Database LinkNP_000567
FunctionThe protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].
Related Pathway
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
MAPK signaling pathway
Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL1B (RC202079, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL1B.

 

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