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Home Antibody All anti-IL17A antibodies

Anti-IL17A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306673
  • Rabbit Polyclonal IL-17 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400795) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for IL17A (NM_002190)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenIL-17 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-17A.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 2 - 4 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interleukin 17A (IL17A)
Alternative NameCTLA8; IL-17; IL-17A; IL17
Database LinkNP_002181
FunctionInterleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-kB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.
Related Pathway
Cytokine-cytokine receptor interaction

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WB Image
Western blot analysis of IL-17 in A-20 lysate with IL-17 antibody at (A) 2 and (B) 4 µg/ml.

 

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