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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-IL17A antibodies

Anti-IL17A Antibody EP434Y

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA300578
  • Rabbit Monoclonal Antibody against IL17A (Clone EP434Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400795) , 20ug
 100µl $325 3-7 Days Add to Shopping Cart
WB(1)
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Also for IL17A (NM_002190)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens interleukin 17A (IL17A)
Synonyms:CTLA8; IL-17; IL-17A; IL17
ImmunogenA recombinant human IL 15 was used an immunogen.
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Clone NameEP434Y IsotypeIgG
Species ReactivityHuman Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1: 1,000-5,000
BackgroundInterleukin 17 (IL-17) is a pro-inflammatory cytokine produced by TCRa/ß+ CD4 CD8 thymocytes, as well as by activated CD4+ and CD4+ CD45RO+ memory T cells (1). IL-17 stimulates the expression of TNFalpha, IL-1 beta, IL-6, and IL-8 (2). In addition, IL-17 is involved in the induction of inducible nitric oxide synthase and cyclooxygenase 2 in chondrocytes (3). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis (4).
Related Pathway
Cytokine-cytokine receptor interaction

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis using anti-IL-17, dilution 1:5,000. (approximately 0.05ug/lane [0.5ug/200ul] of recombinant protein was loaded on the membrane)

 

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