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Home Antibody All anti-IL15 antibodies

Anti-IL15 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319665
  • Rabbit Polyclonal IL-15 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403532) , 20ug
100ug $325 3-7 Days
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WB(1)
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Also for IL15 (NM_000585)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenRabbit polyclonal IL-15 antibody was raised against a 13 amino acid peptide near the center of human IL-15.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 - 2 ug/ml,IHC
BufferIL-15 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification IL-15 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens interleukin 15 (IL15), transcript variant 3
Alternative NameIL-15
Database LinkNP_000576
FunctionIL-15 Antibody: Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.
Related Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway

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WB Image
Western blot analysis of IL-15 in rat spleen tissue lysate with IL-15 antibody at (A) 1 and (B) 2 ug/mL

 

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