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Anti-IL13RA1 Antibody EPR5447(2)
Also for IL13RA1 (NM_001560)
|A synthetic peptide corresponding to residues in the extracellular domain of human IL-13R alpha-1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
|Homo sapiens interleukin 13 receptor, alpha 1 (IL13RA1)|
|CD213A1; IL-13Ra; NR4|
|IL-13R alpha-1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. IL-13R alpha-1 has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4 (1). |
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
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Western blot - Anti-IL13 receptor alpha 1 antibody [EPR5447(2)]; All lanes : Anti-IL13 receptor alpha 1 antibody [EPR5447(2)] at 1/1000 dilution.Lane 1 : HT-29 cell lysates.Lane 2 : A549 cell lysates.Lane 3 : SK-OV-3 cell lysates.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 49 kDa.
Other-Anti-IL13 receptor alpha 1 antibody [EPR5447(2)](ab129188); Equilibrium disassociation constant (KD)..