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Anti-IL13 TRUEMAB Antibody Clone 6D3
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for IL13 (NM_002188)
|Human recombinant protein fragment corresponding to amino acids 36-146 of human IL13 (NP_002179) produced in E.coli.|
|| WB 1:500,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens interleukin 13 (IL13)|
Entrez Gene 3596 Human
|This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]. |
|Secreted ProteinTransmembraneDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathwayFc epsilon RI signaling pathwayAsthma|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL13 (RC216947, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL13.