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Home Antibody All anti-IL10RA antibodies

Anti-IL10RA TRUEMAB Antibody Clone OTI1E5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA506928 IL10RA mouse monoclonal antibody, clone OTI1E5 (formerly 1E5) 100ul $325 In Stock
LC400596 IL10RA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506928 Carrier-free (BSA/glycerol-free) IL10RA mouse monoclonal antibody, clone OTI1E5 (formerly 1E5) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IF(1)
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Also for IL10RA (NM_001558)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human IL10RA(NP_001549) produced in HEK293T cell.
Clone NameClone OTI1E5 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF Suggested Dilutions WB 1:1000, IF 1:100,
Predicted MW Explanation 60.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens interleukin 10 receptor, alpha (IL10RA), transcript variant 1
Alternative NameCD210; CD210a; CDW210A; HIL-10R; IL-10R1; IL10R
Database LinkNP_001549
Entrez Gene 3587 Human
FunctionThe protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009].
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL10RA (RC207020, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL10RA.
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Anti-IL10RA mouse monoclonal antibody (TA506928) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IL10RA(RC207020).
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