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Home Antibody All anti-IKZF3 antibodies

Anti-IKZF3 TRUEMAB Antibody Clone OTI7E11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA804396 IKZF3 mouse monoclonal antibody, clone OTI7E11 (formerly 7E11) 100ul $325 In Stock
LC402225 IKZF3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF804396 Carrier-free (BSA/glycerol-free) IKZF3 mouse monoclonal antibody, clone OTI7E11 (formerly 7E11) 100ug $450 3-4 Days
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WB(1)
IHC(3)
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Also for IKZF3 (NM_012481)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-301 of human IKZF3 (NP_036613) produced in E.coli.
Clone NameClone OTI7E11 IsotypeIgG2b
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
Predicted MW Explanation 57.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens IKAROS family zinc finger 3 (Aiolos) (IKZF3), transcript variant 1
Alternative NameAIO; AIOLOS; ZNFN1A3
Database LinkNP_036613
Entrez Gene 22806 Human
FunctionThis gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IKZF3 (RC207547, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IKZF3.
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-IKZF3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804396)
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-IKZF3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804396)
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Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-IKZF3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804396)
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