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Home Antibody All anti-IGFBP2 antibodies
UltraMAB

Anti-IGFBP2 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA590786 Rabbit Polyclonal IGFBP2 Antibody 100ug $325 2 Weeks
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WB(2)
IHC(3)
ELISA(1)
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Also for IGFBP2 (NM_000597)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the Middle Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman , Monkey Concentration0.76mg/ml
Guaranteed Application *WB, ELISA, IHC Suggested DilutionsWB 1:5000~20000, IHC 1:150, ELISA 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens insulin like growth factor binding protein 2 (IGFBP2), transcript variant 1
Alternative NameIBP2; IGF-BP53
Database LinkNP_000588
Entrez Gene 3485 Human
Entrez Gene 696214 Monkey
FunctionIGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is over expressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The over expression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
Related PathwaySecreted ProteinES Cell Differentiation/IPSAdult stem cellsEmbryonic stem cellsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IGFBP2 (RC202573, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IGFBP2.
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WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-IGFBP2 polyclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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ELISA Image
ELISA: IGFBP2 Antibody
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IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-IGFBP2 Rabbit Polyclonal antibody. (TA590786)
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IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-IGFBP2 Rabbit Polyclonal antibody. (TA590786)
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IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-IGFBP2 Rabbit Polyclonal antibody. (TA590786)
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