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Home Antibody All anti-IGF1R antibodies

Anti-IGF1R PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321219
  • Anti-IGF1R (Phospho-Tyr1165/Tyr1166) Rabbit Polyclonal Antibody
100ul $325 2-3 Weeks
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WB(1)
IF(1)
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Also for IGF1R (NM_000875)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide sequence around phosphorylation site of tyrosine 1165/tyrosine 1166 (T-D-Y(p)-Y(p)-R-K) derived from Human IGF-1R .
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:500-1000, IF: 1:100-200
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens insulin-like growth factor 1 receptor (IGF1R)
Alternative NameCD221; IGFIR; IGFR; JTK13
Database LinkNP_000866
FunctionThis receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
Related Pathway
Adherens junction
Apoptosis
Focal Adhesion
Senescence and Autophagy

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WB Image
Predicted band size: 155 kDa . Positive control: 293 cells treated with insulin lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: 293 cells untreated with insulin lysate Lane2: 293 cells treated with insulin lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
IF Image
Predicted cell location: Cell membrane. Positive control: MCF cells. Recommended dilution: 1/ 100-200.The image is immunofluorescence of methanol-fixed MCF cells using IGF1R (Phospho-Tyr1165/Tyr1166) antibody at dilution 1/100. (Original magnification:×200)

 

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