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 Home All anti-IFT57 antibodies

Anti-IFT57 TrueMAB Antibody clone 4F6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA500918
  • anti-IFT57 (HIPPI) mouse monoclonal antibody, clone 4F6
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402637) , 20ug
 100ul $325 In Stock
CF500918
  • Carrier-free (BSA/glycerol-free) IFT57 mouse monoclonal antibody, clone 4F6
100ug $450 3-4 weeks
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
 30ul
$100
$50*		 In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IHC(4)
IF(1)
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Also for IFT57 (NM_018010)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human IFT57(NP_060480) produced in HEK293T cell.
Clone Nameclone 4F6 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:2000, IHC 1:50, IF 1:100,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target NameHomo sapiens intraflagellar transport 57 homolog (Chlamydomonas) (IFT57)
Alternative NameESRRBL1; HIPPI; MHS4R2
Database LinkNP_060480
FunctionRequired for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1,leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3'present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IFT57 (RC204116, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IFT57.
IHC Image
Immunohistochemical staining of paraffin-embedded breast tissue using anti-IFT57 mouse monoclonal antibody. (TA500918, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-IFT57mouse monoclonal antibody. (TA500918, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-IFT57mouse monoclonal antibody. (TA500918, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-IFT57mouse monoclonal antibody. (TA500918, Dilution 1:50)
IF Image
Anti-IFT57 mouse monoclonal antibody (TA500918) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IFT57(RC204116).

 

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