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Home Antibody All anti-IFT57 antibodies

Anti-IFT57 Antibody 1E1

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301535
  • Mouse Monoclonal Antibody against HIP1 Receptor (1E1)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402637) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
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Also for IFT57 (NM_018010)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHuman HIP1r-TALIN Homology Region (57 kDa).
Clone Name1E1 IsotypeIgG1 kappa
Species Reactivityhuman, rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1: 1000
Buffer

Reference Data

Target NameHomo sapiens intraflagellar transport 57 (IFT57)
Alternative NameESRRBL1; HIPPI; MHS4R2
Database LinkNP_060480
Entrez Gene 55081 Human
Entrez Gene 303968 Rat
FunctionHuntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.
Related PathwayDruggable Genome Huntington's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western Blot analysis of HIP1 protein in HeLa cell and rat brain lysates,

 

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