Home Antibody All anti-IDH2 antibodies
Also for IDH2 (NM_002168)
|Recombinant fragment corresponding to a region within amino acids 56 and 345 of IDH2 (Uniprot ID#P48735)|
|Human, Mouse (Predicted: Rhesus Monkey)
||Lot dependent; please refer to CoA along with shipment
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Rhesus Monkey (100%)
|Homo sapiens isocitrate dehydrogenase 2 (NADP+), mitochondrial (IDH2), transcript variant 1|
|D2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH|
Entrez Gene 3418 Human
Entrez Gene 269951 Mouse
Entrez Gene 701480 Monkey
|Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq]|
| Citrate cycle (TCA cycle)Glutathione metabolismMetabolic pathways|
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Sample (50 ug of whole cell lysate). A: Mouse brain. 10% SDS PAGE. TA308664 diluted at 1:1000.
Sample(30 ug of whole cell lysate). A:MOLT4. 7.5% SDS PAGE. TA308664 diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded normal gastric epithelium (gland), using IDH2(TA308664) antibody at 1:100 dilution.