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Home Antibody All anti-HVCN1 antibodies

Anti-HVCN1 Antibody Polyclonal

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SKU Description Amount Price Availability*  
TA320047 Rabbit Polyclonal HVCN1 Antibody 100ug $325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenHVCN1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human HVCN1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferHVCN1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification HVCN1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens hydrogen voltage gated channel 1 (HVCN1), transcript variant 1
Alternative NameHV1; VSOP
Database LinkNP_001035196
Entrez Gene 84329 Human
Entrez Gene 74096 Mouse
Entrez Gene 304485 Rat
FunctionHVCN1 Antibody: HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of HVCN1 in human spleen tissue lysate with HVCN1 antibody at (A) 0.5 and (B) 1 ug/mL.
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Immunohistochemistry of HVCN1 in rat spleen tissue with HVCN1 antibody at 5 ug/mL.
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