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Home Antibody All anti-HTR1B antibodies

Anti-HTR1B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302601
  • Goat Polyclonal Antibody against Serotonin receptor 1B / HTR1B
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424477) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-SNEDFKQAFHK, from the C Terminus of the protein sequence according to NP_000854.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Cat, Dog, Pig, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:8,000. WB: 1-3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled (HTR1B)
Alternative Name5-HT1B; 5-HT1DB; HTR1D2; HTR1DB; S12
Database LinkNP_000854
Entrez Gene 3351 Human
Entrez Gene 15551 Mouse
Entrez Gene 25075 Rat
Entrez Gene 403741 Dog
FunctionThe neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of 4 main groups, 5-HT-1, 5-HT-2, 5-HT-3, and 5-HT4, subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM].
Related PathwayGPCRTransmembraneDruggable Genome Neuroactive ligand-receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302601 (2µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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