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Home Antibody All anti-HSPB8 antibodies

Anti-HSPB8 TRUEMAB Antibody Clone OTI1E3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA501210 HSPB8 (Hsp22) mouse monoclonal antibody, clone OTI1E3 (formerly 1E3) 100ul $379 In Stock
LC415329 HSPB8 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501210 Carrier-free (BSA/glycerol-free) HSPB8 mouse monoclonal antibody, clone OTI1E3 (formerly 1E3) 100ug $450 3-4 weeks
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WB(2)
IF(1)
FC(2)
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Also for HSPB8 (NM_014365)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human HSPB8(NP_055180) produced in HEK293T cell.
Clone NameClone OTI1E3 IsotypeIgG2a
Species ReactivityHuman, Rat Concentration0.88 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:500~2000, IF 1:100, FLOW 1:100
Predicted MW Explanation 21.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens heat shock 22kDa protein 8 (HSPB8)
Alternative NameCMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22
Database LinkNP_055180
Entrez Gene 26353 Human
Entrez Gene 113906 Rat
FunctionThe protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSPB8 (RC201040, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HSPB8.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-HSPB8 monoclonal antibody.
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Anti-HSPB8 mouse monoclonal antibody (TA501210) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HSPB8(RC201040 ).
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HEK293T cells transfected with either RC201040 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-HSPB8 antibody(TA501210), and then analyzed by flow cytometry.
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Flow cytometric Analysis of Jurkat cells, using anti-HSPB8 antibody(TA501210),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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