Home Antibody All anti-HSPB8 antibodies
Also for HSPB8 (NM_014365)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 134 and 196 of HSPB8|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens heat shock 22kDa protein 8 (HSPB8)|
|CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22|
|The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq]|
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Sample(30 ug whole cell lysate) A:293T whole cell lysate B:A431 (anti-HSPB8 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded LUNG SCC, using HSP22(anti-HSPB8 antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using HSPB8(anti-HSPB8 antibody) antibody at 1:200 dilution.