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Home Antibody All anti-HSPB8 antibodies

Anti-HSPB8 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308596
  • Rabbit Polyclonal antibody to HSP22 (heat shock 22kDa protein 8)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC415329) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for HSPB8 (NM_014365)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 134 and 196 of HSP22 (Uniprot ID#Q9UJY1)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Dog, Rhesus Monkey, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (85%), Rat (85%), Dog (100%), Rhesus Monkey (100%), Bovine (92%)

Reference Data

Target NameHomo sapiens heat shock 22kDa protein 8 (HSPB8)
Alternative NameCMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22
Database LinkNP_055180
Entrez Gene 26353 Human
Entrez Gene 80888 Mouse
Entrez Gene 113906 Rat
Entrez Gene 574341 Monkey
Entrez Gene 403553 Dog
FunctionThe protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq]
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug whole cell lysate). A:293T whole cell lysate. B:A431. 12% SDS PAGE. TA308596 diluted at 1:1000
IHC Image
Immunohistochemical analysis of paraffin-embedded LUNG SCC, using HSP22(TA308596) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using HSPB8(TA308596) antibody at 1:200 dilution.

 

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