Home Antibody All anti-HSPB8 antibodies
Also for HSPB8 (NM_014365)
|Synthetic peptide corresponding to a region within amino acids 134 and 196 of HSP22 (Uniprot ID#Q9UJY1)|
|Human (Predicted: Mouse, Rat, Dog, Rhesus Monkey, Bovine)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (85%), Rat (85%), Dog (100%), Rhesus Monkey (100%), Bovine (92%)
|Homo sapiens heat shock 22kDa protein 8 (HSPB8)|
|CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22|
Entrez Gene 26353 Human
Entrez Gene 80888 Mouse
Entrez Gene 113906 Rat
Entrez Gene 574341 Monkey
Entrez Gene 403553 Dog
|The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq]|
|Protein KinaseDruggable Genome |
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Sample(30 ug whole cell lysate). A:293T whole cell lysate. B:A431. 12% SDS PAGE. TA308596 diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded LUNG SCC, using HSP22(TA308596) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using HSPB8(TA308596) antibody at 1:200 dilution.