Home Antibody All anti-HSP90AB1 antibodies
Also for HSP90AB1 (NM_007355)
|Purified recombinant human Hsp90beta.|
|Human, Rat, Mouse
||WB, ELISA, IP, IHC
|PBS pH7.4, 50% glycerol, 0.09% sodium azide, 0.09% sodium azide|
|Homo sapiens heat shock protein 90kDa alpha (cytosolic), class B member 1 (HSP90AB1), transcript variant 2|
|D6S182; HSP84; HSP90B; HSPC2; HSPCB|
|HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]. |
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Western blot analysis of Hsp90Beta in a cell line mix, using a 1:2000 dilution of SPC-177.
Analysis showing the specificity of SPC-177. Left: 2ug of Hsp90Alpha, Right: 2ug Hsp90Beta.
Hsp90Beta visualized using SPC-177, tested on Bouin's fixed, paraffin embedded backskin sections of transgenic mice.