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Home Antibody All anti-HSF4 antibodies

Anti-HSF4 Antibody EP1719Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310597
  • Rabbit Monoclonal antibody against HSF4 (Isoform a)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400428) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for HSF4 (NM_001040667)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human HSF4 was used as an immunogen.
Clone NameEP1719Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1,000 - 10,000; FC: 1:20;
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens heat shock transcription factor 4 (HSF4), transcript variant 2
Alternative NameCTM; CTRCT5
Database LinkNP_001035757
Entrez Gene 3299 Human
FunctionHeat shock transcription factors (HSFs) mediate the inducible transcriptional response of genes that encode heat shock proteins and molecular chaperones. HSF4 a novel member of the HSF family that shares properties with other members of the HSF family yet appears to be functionally distinct. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. HSF4 represents a novel HSF that exhibits tissue-specific expression and functions to repress the expression of genes encoding heat shock proteins and molecular chaperones. HSF4 is preferentially expressed in the human heart, brain, skeletal muscle, and pancreas (1). The expression of heat shock genes is controlled at the level of transcription by members of the heat shock transcription factor family in vertebrates. HSF4 is characterized by its lack of a suppression domain that modulates formation of DNA-binding homotrimer (2)
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Anti-HSF4 antibody [EP1719Y] (TA310597) at 1/10000 dilution + HeLa cell lysate at 10 ug. Secondary: HRP goat anti-rabbit at 1/2000 dilution
IHC Image
Immunohistochemical analysis of human muscle with TA310597 at 1/50 - 1/100 dilution

 

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