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Home Antibody All anti-HSF2 antibodies

Anti-HSF2 Antibody EPR1715Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300942
  • Rabbit Monoclonal Antibody against HSF2 (Clone EPR1715Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401434) , 20ug
100ul 325 In Stock
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WB(1)
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Also for HSF2 (NM_004506)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human HSF2 was used as an immunogen
Clone NameEPR1715Y IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:500; FC: 1:30; ICC/IF: 1:50
BufferDoes not react with Mouse, Rat. Is unsuitable for IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens heat shock transcription factor 2 (HSF2), transcript variant 1
Alternative NameHSF 2; HSTF 2
Database LinkNP_004497
FunctionThe heat shock response is transcriptionally regulated by an evolutionarily conserved protein termed heat shock factor (HSF). It appears that there is a human heat shock factor gene family and that at least two separate but related HSF proteins regulate the stress response in humans (1). HSF2, one of the heat shock transcription factors in mammalian cells, is localized to the cytoplasm during normal growth and moves to the nucleus upon activation. Heat shock transcription factors in metazoans contain four hydrophobic heptad repeat sequences, three in the amino terminus and one in the carboxy terminus, which are predicted to form alpha-helical coiled-coil structures analogous to the leucine zipper. It is believed that zipper domains can regulate subcellular localization (2). The promoter regions of some genes, such as the stress-inducible hsp70i gene that codes for a heat shock protein, remain uncompacted, a phenomenon called bookmarking. It has been shown that hsp70i bookmarking is mediated by transcription factor HSF2 (3)
Related Pathway

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WB Image
Western blot - HSF2 antibody [EPR1715Y]; Anti-HSF2 antibody [EPR1715Y] at 1/500 dilution + Hela cell lysate at 10 µg.Secondary.Goat anti-rabbit HRP labeled at 1/2000 dilution.Predicted band size : 60 kDa.Observed band size : 60 kDa.

 

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