Homo sapiens heat shock transcription factor 1 (HSF1)
Synonyms:
HSTF1
Immunogen
A phospho specific peptide corresponding to residues surrounding Ser326 of human HSF1 was used as an immunogen. This antibody detects HSF1 phosphorylated on Ser326.
Buffer
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene. [provided by RefSeq].
Related Pathway
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Western blot analysis on HeLa cell lysates using anti-Phospho-HSF1 (pS326) RabMAb (TA303540), 1:100,000 dilution. Cells were either (A) untreated (B) treated with heat (44ºC)