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Home Antibody All anti-HRAS antibodies

Anti-HRAS Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308498
  • Rabbit polyclonal antibody to H-Ras (v-Ha-ras Harvey rat sarcoma viral oncogene homolog)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC430451) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 111 and 176 of H-Ras
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:500; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens Harvey rat sarcoma viral oncogene homolog (HRAS), transcript variant 2
Alternative NameC-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; p21ras; RASH1
Database LinkNP_789765
FunctionThis gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq]
Related Pathway
EGFR1 Signaling Pathway
Focal Adhesion
Hemostasis
MAPK signaling pathway
Melanogenesis
Senescence and Autophagy
TGF Beta Signaling Pathway

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WB Image
A: Hela B: HepG2 C: Molt-4 (anti-HRAS antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded OVCAR3 xenograft , using H-Ras (anti-HRAS antibody) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using H-Ras (anti-HRAS antibody) antibody at 1:200 dilution.

 

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