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Home Antibody All anti-HRAS antibodies

Anti-HRAS Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308498
  • Rabbit polyclonal antibody to H-Ras (v-Ha-ras Harvey rat sarcoma viral oncogene homolog)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC430451) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
IHC(1)
IF(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 111 and 189 of H-Ras (Uniprot ID#P01112)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Xenopus laevis, Xenopus Tropicalis, Chicken, Rhesus Monkey, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Xenopus laevis (100%), Xenopus Tropicalis (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (88%)

Reference Data

Target NameHomo sapiens Harvey rat sarcoma viral oncogene homolog (HRAS), transcript variant 2
Alternative NameC-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; p21ras; RASH1
Database LinkNP_789765
Entrez Gene 3265 Human
Entrez Gene 698830 Monkey
FunctionThis gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq]
Related PathwayDruggable Genome MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwayEndocytosisAxon guidanceVEGF signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
H-Ras antibody detects HRAS protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. B. 30 ug Rat2 whole cell lysate/extract. 12 % SDS-PAGE. H-Ras antibody (TA308498) dilution: 1:1000
WB Image
Sample (30 ug of whole cell lysate). A: Hela. B: Hep G2 . C: Molt-4 . 12% SDS PAGE. TA308498 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded OVCAR3 xenograft , using H-Ras (TA308498) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using H-Ras (TA308498) antibody at 1:200 dilution.

 

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