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UltraMAB

HP UltraMAB Antibody, Clone UMAB10

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations Related Products Product Documents
SKU Description Datasheet Price Availability*  
UM500010
  • anti-HP mouse monoclonal antibody, clone UMAB10, 100 ul
468 In Stock Add to Shopping Cart
UM570010
  • anti-HP mouse monoclonal antibody, clone UMAB10, 30 ul
$120 In Stock Add to Shopping Cart
WB(2)
IHC(11)
IF(1)
10K-CHIP(1)
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Also for HP (NM_005143)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens haptoglobin (HP), transcript variant 1
SynonymsBP; HP2ALPHA2; HPA1S
ImmunogenFull length human recombinant protein of human HP (NP_005134) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone UMAB10 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF, 10K-CHIP Suggested DilutionsWB 1:500~2000, IF 1:100
BackgroundThis gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-HP monoclonal antibody (Clone UMAB10) at 1:500.
WB Image
Western Blot analysis of 10 different human tissue lysates (10ug) by using anti-HP monoclonal antibody (clone UMAB10, 1:500)
IHC Image
Immunohistochemical staining of paraffin-embedded breast tissue using anti-HP mouse monoclonal antibody. (Clone UMAB10, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-HP mouse monoclonal antibody. (Clone UMAB10, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded colon tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded lung tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of lung tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of pancreas tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of prostate tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, Dilution 1:100)
IF Image
Immunofluorescent staining of HepG2 cells using anti-HP mouse monoclonal antibody (UM500010, green). Actin filaments were labeled with TRITC-phalloidin (red), and nuclear with DAPI (blue). The three-color overlay image is located at the bottom-right corner.
10K-CHIP Image
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-HP mouse monoclonal antibody (Clone UMAB10). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification. These data show that UltraMAB anti-HP (Clone UMAB10) very specifically recognizes HP antigen on OriGene protein microarray chip.

 

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