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Anti-HP TRUEMAB Antibody Clone OTI2B11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA501675 anti-HP mouse monoclonal antibody, clone OTI2B11 (formerly 2B11) 100ul 325
In Stock
LC401576 HP HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501675 Carrier-free (BSA/glycerol-free) HP mouse monoclonal antibody, clone OTI2B11 (formerly 2B11) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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OriGene Data

ImmunogenFull length human recombinant protein of human HP (NP_005134) produced in HEK293T cell.
Clone NameClone OTI2B11 IsotypeIgG1
Species ReactivityHuman Concentration0.56 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:500~2000,
Predicted MW Explanation 43.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens haptoglobin (HP), transcript variant 1
Alternative NameBP; HP2ALPHA2; HPA1S
Database LinkNP_005134
Entrez Gene 3240 Human
FunctionThis gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwaySecreted ProteinTransmembraneProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HP (RC223612, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HP.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-HP monoclonal antibody.


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