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Home Antibody All anti-HP antibodies

Anti-HP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309542
  • Goat Polyclonal Antibody against HP beta chain
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401576) , 20ug
100ug $325 3-7 Days
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WB(1)
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Also for HP (NM_005143)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-STVPEKKTPKSP, from the internal region of the protein sequence according to NP_005134.1; NP_001119574.1.
Clone Name Isotype
Species ReactivityHuman, Dog, porcine Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 0.1-0.3ug/ml
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Reference Data

Target NameHomo sapiens haptoglobin (HP), transcript variant 1
Alternative NameBP; HP2ALPHA2; HPA1S
Database LinkNP_005134
FunctionThis gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

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WB Image
TA309542 (0.1µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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