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Home Antibody All anti-HP antibodies

Anti-HP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308900
  • Rabbit Polyclonal antibody to Haptoglobin (haptoglobin)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC426644) , 20ug Explanation
100ul 325 3-7 Days
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IHC(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 57 and 406 of Haptoglobin (Uniprot ID#P00738)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.59mg/ml
Guaranteed Application *IHC Suggested DilutionsIHC:1:100-1:1000
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens haptoglobin (HP), transcript variant 2
Alternative NameBP; HP2ALPHA2; HPA1S
Database LinkNP_001119574
Entrez Gene 3240 Human
FunctionThis gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related PathwaySecreted ProteinTransmembraneProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Immunohistochemical analysis of paraffin-embedded Normal gastric, using Haptoglobin(TA308900) antibody at 1:100 dilution.

 

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