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Home Antibody All anti-HNRNPM antibodies

Anti-HNRNPM Antibody 2A6

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Specifications Citations (1) Related Products Product Documents
SKU Description Amount Price Availability*  
TA301557 Mouse Monoclonal Antibody against Heterogenous Nuclear ribonucleoproteins M3/4 (2A6) 100ul $325 2 Weeks
LC403103 HNRNPM HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(2)
IHC(1)
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Also for HNRNPM (NM_031203)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenM19 fusion protein containing full-length human protein.
Clone Name2A6 IsotypeIgG2b kappa
Species Reactivityhuman, mouse, rat, bovine, porcine, rabbit ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000-1: 10,000
BufferAscitic fluid and sodium azide
Purification Ascites

Reference Data

Target NameHomo sapiens heterogeneous nuclear ribonucleoprotein M (HNRNPM), transcript variant 2
Alternative NameCEAR; hnRNP M; HNRNPM4; HNRPM; HNRPM4; HTGR1; NAGR1
Database LinkNP_112480
Entrez Gene 4670 Human
Entrez Gene 76936 Mouse
Entrez Gene 116655 Rat
FunctionProteins that directly bind to nascent RNA polymerase II transcripts, the heterogenous nuclear ribonucleoproteins (hnRNPs), play an important role in both transcript-specific packaging and alternative splicing of pre-mRNAs. A group of abundant hnRNPs, the M1-M4 proteins, appear as a cluster of four proteins. The M proteins are pre-mRNA binding proteins in vivo, and they bind avidly to poly (G) and poly (U) RNA homopolymers in vitro. M proteins are members of the ribonucleoprotein consensus sequence family of RNA-binding proteins with greatest similarity to a hypothetical RNA-binding protein from Saccharomyces cerevisiae. The M proteins also possess an unusual hexapeptide-repeat region rich in methionine and arginine residues (MR repeat motif) that resembles a repeat in the 64kDa subunit of cleavage stimulation factor, which is involved in 3'-end maturation of pre-mRNAs. Proteins immunologically related to M exist in divergent eukaryotes ranging from human to yeast.
Related PathwayDruggable Genome Spliceosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western Blot: hnRNP M Antibody (2A6) TA301557 - Analysis of hnRNP M3-M4 in HeLa cell lysate.
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Figure from citation: Western Blot of HNRNPM protein level by using anti-HNRNPM antibody in human Mes10A cells. View Citation
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Figure from citation: Immunohistochemistry of HNRNPM protein level by using anti-HNRNPM antibody in both DCIS and invasive human breast cancer specimens. View Citation
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