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Anti-HNF1B Antibody EPR6334(2)
Also for HNF1B (NM_000458)
|A synthetic peptide corresponding to residues in human HNF 1 Beta was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens HNF1 homeobox B (HNF1B), transcript variant 1|
|FJHN; HNF-1B; HNF1beta; HNF2; HPC11; LF-B3; LFB3; MODY5; TCF-2; TCF2; VHNF1|
|HNF 1 Beta is a member of the homeodomain-containing superfamily of transcription factors. It binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. It has been shown to function in nephron development, and it regulates development of the embryonic pancreas. Mutations in HNF 1 Beta result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of HNF 1 Beta is altered in some types of cancer (1).|
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Western blot - Anti-TCF2 antibody [EPR6334(2)]; All lanes : Anti-HNF1 beta antibody [EPR6334(2)] at 1/1000 dilution.Lane 1 : Human fetal kidney lysate.Lane 2 : Caco 2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 61 kDa.