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Home Antibody All anti-HMGB2 antibodies

Anti-HMGB2 Antibody EPR6301

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310583
  • Rabbit Monoclonal antibody against HMGB2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC427242) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
Assay(1)
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Also for HMGB2 (NM_001130688)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the N-terminus in human HMGB2 was used as an immunogen.
Clone NameEPR6301 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; ICC: 1:100 - 1:250
Predicted MW Explanation 24 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens high mobility group box 2 (HMGB2), transcript variant 2
Alternative NameHMG2
Database LinkNP_001124160
Entrez Gene 3148 Human
Entrez Gene 97165 Mouse
Entrez Gene 29395 Rat
FunctionHMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. HMGB2 was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination (1).
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-HMGB2 antibody [EPR6301]; All lanes : Anti-HMGB2 antibody [EPR6301] at 1/10000 dilution.Lane 1 : K562 cell lysates.Lane 2 : HeLa cell lysates.Lane 3 : PC12 cell lysates.Lysates/proteins at 10 ug per lane.Secondary.Goat-anti-rabbit HRP at 1/2000 dilution.Predicted band size : 24 kDa.
Assay Image
Other-Anti-HMGB2 antibody [EPR6301](TA310583); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMGB2 antibody [EPR6301]; TA310583, at a 1/250 dilution, staining HMGB2 in paraffin embedded Human breast tissue by Immunohistochemistry.

 

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