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Home Antibody All anti-HMBS antibodies

Anti-HMBS TRUEMAB Antibody Clone OTI3F4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA802669 HMBS mouse monoclonal antibody, clone OTI3F4 (formerly 3F4) 100ul $325 In Stock
LC400069 HMBS HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF802669 Carrier-free (BSA/glycerol-free) HMBS mouse monoclonal antibody, clone OTI3F4 (formerly 3F4) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(5)

OriGene Data

ImmunogenFull length human recombinant protein of human HMBS (NP_000181) produced in HEK293T cell.
Clone NameClone OTI3F4 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000,
Predicted MW Explanation 39.1 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens hydroxymethylbilane synthase (HMBS), transcript variant 1
Alternative NamePBG-D; PBGD; PORC; UPS
Database LinkNP_000181
Entrez Gene 3145 Human
FunctionThis gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Related PathwayDruggable Genome Porphyrin and chlorophyll metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HMBS (RC201362, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HMBS.
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-HMBS mouse monoclonal antibody. (TA802669) Dilution: 1:150
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-HMBS mouse monoclonal antibody. (TA802669) Dilution: 1:150
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-HMBS mouse monoclonal antibody. (TA802669) Dilution: 1:150
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-HMBS mouse monoclonal antibody. (TA802669) Dilution: 1:150
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-HMBS mouse monoclonal antibody. (TA802669) Dilution: 1:150
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