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Home Antibody All anti-HMBS antibodies

Anti-HMBS Antibody EPR8105

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310581
  • Rabbit Monoclonal antibody against HMBS
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400069) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
Assay(1)
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Also for HMBS (NM_000190)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human HMBS was used as an immunogen.
Clone NameEPR8105 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000
Predicted MW Explanation 39 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens hydroxymethylbilane synthase (HMBS), transcript variant 1
Alternative NamePBG-D; PBGD; PORC; UPS
Database LinkNP_000181
Entrez Gene 3145 Human
Entrez Gene 15288 Mouse
Entrez Gene 25709 Rat
FunctionHMBS is a member of the hydroxymethylbilane synthase superfamily. It is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in HMBS are associated with the autosomal dominant disease acute intermittent porphyria (1).
Related PathwayDruggable Genome Porphyrin and chlorophyll metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-HMBS antibody [EPR8105]; All lanes : Anti-HMBS antibody [EPR8105] at 1/1000 dilution.Lane 1 : HepG2 cell lysates .Lane 2 : HeLa cell lysates .Lane 3 : U937 cell lysates .Lane 4 : K562 cell lysates .Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 39 kDa.Observed band size : 42-44 kDa .
Assay Image
Other-Anti-HMBS antibody [EPR8105](TA310581); Equilibrium disassociation constant (KD)..

 

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