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Home Antibody All anti-HIST3H3 antibodies

Anti-HIST3H3 Antibody Y28

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303745
  • Rabbit monoclonal antibody against Histone H3 Acetyl (K9)(Y28)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418646) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for HIST3H3 (NM_003493)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic acetylated peptide corresponding to residues surrounding Lys9 of Histone H3 was used as immunogen. The antibody only detects Histone H3 acetylated on Lysine 9.
Clone NameY28 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500; IHC: 1:50 - 1:100; ICC: 1:250; IP: 1:40
Predicted MW Explanation 15 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction

Reference Data

Target NameHomo sapiens histone cluster 3, H3 (HIST3H3)
Alternative NameH3.4; H3/g; H3FT; H3t
Database LinkNP_003484
Entrez Gene 8290 Human
Entrez Gene 691496 Rat
FunctionHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Related Pathway Systemic lupus erythematosus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Histone H3 antibody [Y28]; All lanes : Anti-Histone H3 (acetyl K9) antibody [Y28] at 1/500 dilution.Lane 1 : Untreated NIH 3T3 cell lysate.Lane 2 : NIH 3T3 cell lysate treated with TSA.Predicted band size : 15 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Histone H3 antibody [Y28]; Immunohistochemical analysis of paraffin-embedded human lung carcinoma using TA303745 at 1/50 - 1/100

 

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