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Anti-HHEX Antibody EPR3361
Also for HHEX (NM_002729)
|A synthetic peptide corresponding to residues in human Hex was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:2000; IP: 1:40; ICC: 1:100 - 1:250; FC: 1:20
|Does not react with Mouse, Rat. Is unsuitable for IHC-P.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for IHC-P.
|Homo sapiens hematopoietically expressed homeobox (HHEX)|
|HEX; HMPH; HOX11L-PEN; PRH; PRHX|
|Hex, the hematopoietically-expressed homeobox protein (proline-rich homeodomain protein/PRH) is a transcription factor that is important in the control of cell proliferation and differentiation and in the regulation of multiple processes in embryonic development. Hex contains two domains that can independently bring about transcriptional repression. The Hex homeodomain represses transcription by binding to TATA box sequences, whereas the proline-rich N-terminal domain of Hex can repress transcription when attached to a heterologous DNA-binding domain (1). Hex is expressed in primitive endoderm, in some endoderm-derived tissues and in endothelial and hematopoietic precursors. Expression is extinguished during terminal differentiation of endothelial and hematopoietic cells as well as in adult lung (2). |
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Western blot - Hex antibody [EPR3361]; All lanes : Anti-Hex antibody [EPR3361] at 1/2000 dilution.Lane 1 : MCF7 cell lysate.Lane 2 : A549 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 30 kDa.Observed band size : 30 kDa.