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Home Antibody All anti-HHATL antibodies

Anti-HHATL Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319975 Rabbit Polyclonal HHATL Antibody 100ug $325 3-7 Days
LC412203 HHATL HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenHHATL antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human HHATL.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 2.5 ug/mL
BufferHHATL Antibody is supplied in PBS containing 0.02% sodium azide.
Purification HHATL Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens hedgehog acyltransferase-like (HHATL), transcript variant 1
Alternative NameC3orf3; GUP1; MBOAT3; MSTP002; OACT3
Database LinkNP_065758
Entrez Gene 57467 Human
Entrez Gene 74770 Mouse
Entrez Gene 301073 Rat
FunctionHHATL Antibody: The Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL), also known at the mammalian glycerol uptake/transporter 1 (Gup1) is a homolog of the S. cerevisiae Gup1. It is an endoplasmic reticulum (ER) membrane protein that co-localizes with the mammalian hedgehog acyltransferse Skn and interferes with its N-terminal palmitoylation of Sonic hedgehog (SHH), suggesting that HHATL acts as a negative regulator for N-terminal palmitoylation of SHH. HHATL is highly expressed in normal skin, but becomes down-regulated in skin squamous cell carcinoma, suggesting it may play a role in its development.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of HHATL in 3T3 cell lysate with HHATL antibody at 1 ug/mL.

IHC Image
Immunohistochemistry of HHATL in human skin tissue with HHATL antibody at 2.5 ug/mL.

IF Image
Immunofluorescence of HHATL in human skin tissue with HHATL antibody at 20 ug/mL.


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