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Home Antibody All anti-HES1 antibodies

Anti-HES1 TRUEMAB Antibody Clone OTI1B5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA504046 HES1 mouse monoclonal antibody, clone OTI1B5 (formerly 1B5) 100ul $325 In Stock
LC417251 HES1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504046 Carrier-free (BSA/glycerol-free) HES1 mouse monoclonal antibody, clone OTI1B5 (formerly 1B5) 100ug $450 3-4 weeks
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WB(1)
IHC(4)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human HES1(NP_005515) produced in HEK293T cell.
Clone NameClone OTI1B5 IsotypeIgG2b
Species ReactivityHuman Concentration0.99 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:500~2000, IHC 1:150, IF 1:100,
Predicted MW Explanation 29.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens hes family bHLH transcription factor 1 (HES1)
Alternative NamebHLHb39; HES-1; HHL; HRY
Database LinkNP_005515
Entrez Gene 3280 Human
FunctionThis protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. [provided by RefSeq, Jul 2008].
Related PathwayStem cell relevant signaling - DSL/Notch pathwayES Cell Differentiation/IPSAdult stem cellsCancer stem cellsTranscription FactorsDruggable Genome Notch signaling pathwayMaturity onset diabetes of the young

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HES1 (RC211709, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-HES1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504046)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-HES1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504046)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-HES1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504046)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-HES1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504046)
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Anti-HES1 mouse monoclonal antibody (TA504046) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HES1(RC211709).
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