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Home Antibody All anti-HES1 antibodies

Anti-HES1 CONJUGATED Antibody Clone OTI4H1

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SKU Description Amount Price Availability*  
TA400011
  • Anti-HES1 mouse mAb, clone OTI4H1, DyLight488 conjugated
100 ul $325 In Stock

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FC(1)

OriGene Data

ImmunogenRecombinant protein expressed in E.coli corresponding to amino acids 1-280 of human HES1
Clone NameClone OTI4H1 IsotypeIgG1
Species ReactivityHuman Concentration0.52 mg/ml
Guaranteed Application *FC Suggested DilutionsFC: 1:100
Predicted MW Explanation 29.4 kDa
BufferPBS (pH7.4) containing 50% glycerol, 0.1% BSA and 0.02% NaN3

Reference Data

Target NameHomo sapiens hes family bHLH transcription factor 1 (HES1)
Alternative NamebHLHb39; HES-1; HHL; HRY
Database LinkNP_005515
FunctionThis protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
Related PathwayStem cell relevant signaling - DSL/Notch pathwayES Cell Differentiation/IPSAdult stem cellsCancer stem cellsTranscription FactorsDruggable Genome Notch signaling pathwayMaturity onset diabetes of the young

* Availability is in business days
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HEK293T cells were transfected with pCMV6-ENTRY control (PS01, left panel) or HES1 cDNA (right panel) and incubated for 48 hours after transfection. The cells were detached, fixed with 2% formaldehyde for 30 min, permeabilized with 0.1% trixon-X100, and then stained with PE-labeled HES1 antibodies (TA400011).
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