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Home Antibody All anti-HDAC8 antibodies

Anti-HDAC8 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319106
  • Rabbit polyclonal anti-HDAC8 antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC432831) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for HDAC8 (NM_001166418)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenE. coli-expressed recombinant human HDAC8
Clone Name IsotypeRabbit IgG
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens histone deacetylase 8 (HDAC8), transcript variant 2
Alternative NameCDA07; CDLS5; HD8; HDACL1; MRXS6; RPD3; WTS
Database LinkNP_001159890
FunctionHuman Histone Deacetylase 8 (HDAC8) is a member of the class I Histone Deacetylases. HDACs are important enzymes for the transcriptional regulation of gene expression in eukaryotic cells. HDACs catalyze the removal of acetyl groups from lysines near the N-termini of histones. Human HDACs have been implicated in a variety of human diseases such as cardiomyopathy, osteodystrophy, neurodegenerative disorders, aging and cancer. Expression of HDAC8 is restricted to cells showing smooth muscle differentiation in normal human tissue and is a novel marker of smooth muscle differentiation. Like other class I and II HDAC members, the activity of HDAC8 is sensitive to HDAC inhibitor Trichostatin A (TSA).
Related Pathway

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WB Image
Western blot analysis using recombinant human HDAC8. Lane 1: 30 ng, Lane 2: 60 ng, Lane 3: 120 ng, Lane 4: 250 ng.

 

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