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Anti-HDAC3 Antibody EP462Y
Also for HDAC3 (NM_003883)
|A synthetic peptide corresponding to residues near the N-terminus of Histone deacetylase 3 was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:2000; IHC-P: 1:100 - 1:250; ICC: 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens histone deacetylase 3 (HDAC3)|
|HD3; RPD3; RPD3-2|
|Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq]. |
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Western blot - Anti-HDAC3 [EP462Y] antibody; Anti-HDAC3 [EP462Y] antibody at 1/2000 dilution + HeLa cell lysate at 10 µg.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 49 kDa.Observed band size : 49 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HDAC3 [EP462Y] antibody; ab76295, at a 1/100-1/250 dilution, staining human HDAC3 in breast carcinoma, by Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue.