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Anti-HDAC1 TRUEMAB Antibody Clone OTI2D2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA501999 HDAC1 mouse monoclonal antibody, clone OTI2D2 (formerly 2D2) 100ul 325
In Stock
LC417624 HDAC1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501999 Carrier-free (BSA/glycerol-free) HDAC1 mouse monoclonal antibody, clone OTI2D2 (formerly 2D2) 100ug $450 3-4 weeks
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Also for HDAC1 (NM_004964)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human HDAC1 (NP_004955) produced in HEK293T cell.
Clone NameClone OTI2D2 IsotypeIgG1
Species ReactivityHuman Concentration0.55 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100
Predicted MW Explanation 54.9 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens histone deacetylase 1 (HDAC1)
Alternative NameGON-10; HD1; RPD3; RPD3L1
Database LinkNP_004955
Entrez Gene 3065 Human
FunctionHistone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq].
Related PathwayStem cell relevant signaling - DSL/Notch pathwayStem cell - PluripotencyAdult stem cellsTranscription FactorsDruggable Genome Cell cycleNotch signaling pathwayHuntington's diseasePathways in cancerChronic myeloid leukemia

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HDAC1 (RC201745, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HDAC1.

IF Image
Anti-HDAC1 mouse monoclonal antibody (TA501999) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HDAC1(RC201745).

FC Image
HEK293T cells transfected with either RC201745 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-HDAC1 antibody(TA501999), and then analyzed by flow cytometry.


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