TIM 3 (HAVCR2) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB 1:500 - 1:1000 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human HAVCR2 |
Formulation | Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 33 kDa |
Gene Name | hepatitis A virus cellular receptor 2 |
Database Link | |
Background | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
Synonyms | CD366; HAVcr-2; KIM-3; Tim-3; TIM3; TIMD-3; TIMD3 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Documents
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.