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Home Antibody All anti-Gria2 antibodies

Anti-Gria2 Antibody S21-32

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SKU Description Amount Price Availability*  
TA326535 Mouse Monoclonal Anti-GluR2 Antibody 100µg $325 3-7 Days
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WB(1)
IHC(2)

OriGene Data

ImmunogenFusion protein amino acids 834-883 (cytoplasmic C-terminus) of rat GluR2
Clone NameS21-32 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1mg/mL
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
BufferPBS pH7.4, 50% glycerol
Purification Protein G Purified
Note Detects ~90kDa.

Reference Data

Target NameRattus norvegicus glutamate receptor, ionotropic, AMPA 2 (Gria2), transcript variant 1
Alternative NameGluA2; gluR-B; GluR-K2; GluR2
Database LinkNP_058957
Entrez Gene 2891 Human
Entrez Gene 14800 Mouse
Entrez Gene 29627 Rat
FunctionThe AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers . GluR2 is possibly the most important AMPA receptor subunit, responsible for AMPA receptor rectifying properties, control of ion flow and in particular, the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2 form, containing a critical arginine residue in the transmembrane region 2 domain, thereby rendering native AMPA receptors impermeable to calcium .
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of GluR2 on rat brain membrane tissues using a 1:1000 dilution of the antibody
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IHC analysis of GluR2 using the antibody,tested on mouse cerebellum. Staining of neurons and fibers.
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IHC analysis of GluR2 using the antibody,tested on mouse cerebellum. Staining of hippocampus: only some neurons appear to be positive to the antibody.
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