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Anti-Gria1 TRUEMAB Antibody S355-1
Also for Gria1 (NM_031608)
|Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1, |
|PBS pH7.4, 50% glycerol, 0.1% sodium azide|
|Protein G Purified
|Detects ~100kDa. Does not cross-react with GluR2.
|Rattus norvegicus glutamate receptor, ionotropic, AMPA 1 (Gria1)|
|Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists . GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration .|
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