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Anti-GZMB TRUEMAB Antibody Clone 4E4
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for GZMB (NM_004131)
|Human recombinant protein fragment corresponding to amino acids 21-247 of human GZMB(NP_004122) produced in E.coli.|
|WB, IHC, IF
|| WB 1:2000, IHC 1:150, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB)|
|CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT|
|Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]. |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GZMB (RC206495, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GZMB.
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-GZMB mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505931)
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-GZMB mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505931)
Anti-GZMB mouse monoclonal antibody (TA505931) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GZMB(RC206495).