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Home Antibody All anti-GZMB antibodies

Anti-GZMB TRUEMAB Antibody Clone 4E4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA505931
  • GZMB (Granzyme B) mouse monoclonal antibody, Clone 4E4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401332) , 20ug Explanation
100ul 379 In Stock
CF505931
  • Carrier-free (BSA/glycerol-free) GZMB mouse monoclonal antibody,clone 4E4
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(1)
IHC(2)
IF(1)
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Also for GZMB (NM_004131)
cDNA Clone shRNA/siRNA Protein/Lysate Antibody Assay

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 21-247 of human GZMB(NP_004122) produced in E.coli.
Clone NameClone 4E4 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:2000, IHC 1:150, IF 1:100,
Predicted MW Explanation 25.5 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB)
Alternative NameCCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT
Database LinkNP_004122
Entrez Gene 3002 Human
FunctionCytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008].
Related PathwayProteaseDruggable Genome Natural killer cell mediated cytotoxicityType I diabetes mellitusAutoimmune thyroid diseaseAllograft rejectionGraft-versus-host disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GZMB (RC206495, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GZMB.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-GZMB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505931)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-GZMB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505931)
IF Image
Anti-GZMB mouse monoclonal antibody (TA505931) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GZMB(RC206495).

 

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