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Home Antibody All anti-GUCY1A3 antibodies

Anti-GUCY1A3 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302112 Rabbit Polyclonal Antibody against GUCY1A3 (N-term) 100ug $325 In Stock
LC400301 GUCY1A3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(2)
IHC(1)
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Also for GUCY1A3 (NM_000856)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenThis Guanylyl Cyclase alpha 1 (GUCY1A3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-300 amino acids from the N-terminal region of human Guanylyl Cyclase alpha 1 (GUCY1A3).
Clone Name IsotypeRabbit Ig
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000, IHC: 1:10~50
Predicted MW Explanation 77452 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens guanylate cyclase 1, soluble, alpha 3 (GUCY1A3), transcript variant 1
Alternative NameGC-SA3; GUC1A3; GUCA3; GUCSA3; GUCY1A1; MYMY6
Database LinkNP_000847
Entrez Gene 2982 Human
FunctionSoluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.
Related PathwayDruggable Genome Purine metabolismVascular smooth muscle contractionGap junctionLong-term depression

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of GUCY1A3 (arrow) using GUCY1A3 Antibody (N-term) (Cat.#TA302112). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GUCY1A3 gene (Lane 2) (Origene Technologies).
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Western blot analysis of anti-GUCY1A3 Pab (Cat. #TA302112) in mouse brain tissue lysate (35ug/lane). GUCY1A3(arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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