Anti-GTF2F2 Antibody, EPR7584

Also for GTF2F2 (NM_004128)

Gene Name	Homo sapiens general transcription factor IIF, polypeptide 2, 30kDa (GTF2F2)
Synonyms:	BTF4; RAP30; TF2F2; TFIIF
Immunogen	A synthetic peptide corresponding to residues in human TFIIF was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR7584	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:1,000 - 10,000; ICC: 1:100 - 250; IP: 1:10 - 100; FC: 1:100 - 500;
Background	TFIIF functions in both transcription initiation and elongation and is one of three general factors, TFIIB, TFIIE, and TFIIF, that directly binds RNA polymerase II (Pol II). TFIIF facilitates Pol II incorporation into a PIC intermediate-containing promoter DNA, TBP, and TFIIB and is required for subsequent recruitment of TFIIE and TFIIH. TFIIF also has functions in open complex formation, transcription start site selection, promoter escape, stabilization of an RNA–DNA hybrid within Pol II, and, along with TFIIS, stimulates elongation by purified Pol II (1).
Related Pathway

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WB Image

Western blot analysis on (A) HeLa and (B) 293T cell lysates using anti-TFIIF RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human cervical carcinoma tissue using anti-TFIIF RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-TFIIF RabMAb.

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Anti-GTF2F2 Antibody EPR7584

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