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Home Antibody All anti-GSTP1 antibodies

Anti-GSTP1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306508 Rabbit Polyclonal GSTP1 Antibody 100ug $325 3-7 Days
LC400300 GSTP1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for GSTP1 (NM_000852)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenGSTP1 antibody was raised against a 14 amino acid peptide from near the center of human GSTP1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens glutathione S-transferase pi 1 (GSTP1)
Alternative NameDFN7; FAEES3; GST3; GSTP; HEL-S-22; PI
Database LinkNP_000843
Entrez Gene 2950 Human
Entrez Gene 14870 Mouse
Entrez Gene 24426 Rat
FunctionGlutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism (i.e., the metabolism of environmental mutagens and carcinogens) and may play a role in susceptibility to cancer. More recent experiments have suggested that differential expression of GSTP1 also contributes to the sensitivity of xenobiotics in the substantia nigra and may influence the pathogenesis of reactive oxygen species-induced neurological disorders such as Parkinson’s disease. CpG island hypermethylation of the GSTP1 promoter leading to the silencing of the GSTP1 gene has also been linked to cancer.
Related PathwayDruggable Genome Glutathione metabolismMetabolism of xenobiotics by cytochrome P450Drug metabolism - cytochrome P450Pathways in cancerProstate cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of GSTP1 in Jurkat cell lysate with GSTP1 antibody at (A) 0.5 and (B) 1 ug/ml.
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Immunohistochemical staining of human lung tissue using GSTP1 antibody at 2.5 ug/ml.
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