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Anti-GSTA4 TRUEMAB Antibody Clone OTI3F5
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for GSTA4 (NM_001512)
|Full length human recombinant protein of human GSTA4 (NP_001503) produced in HEK293T cell.|
|WB, IHC, FC
||WB: 1:500-1:2000, FLOW: 1:100, IHC: 1:50-1:150
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens glutathione S-transferase alpha 4 (GSTA4)|
Entrez Gene 2941 Human
|Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. |
| Glutathione metabolismMetabolism of xenobiotics by cytochrome P450Drug metabolism - cytochrome P450|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GSTA4 (RC202130, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GSTA4.
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-GSTA4 mouse monoclonal antibody at 1:150 (TA501903)
Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-GSTA4 mouse monoclonal antibody at 1:150 (TA501903)
Flow cytometric Analysis of Hela cells, using anti-GSTA4 antibody(TA501903),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).