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Home Antibody All anti-GSTA2 antibodies

Anti-GSTA2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308025
  • Rabbit Polyclonal antibody to GSTA2 (glutathione S-transferase alpha 2)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424488) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for GSTA2 (NM_000846)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 196 of GSTA2 (Uniprot ID#P09210)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Monkey, Pig) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 26kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Monkey (92%), Pig (82%)

Reference Data

Target NameHomo sapiens glutathione S-transferase alpha 2 (GSTA2)
Alternative NameGST2; GSTA2-2; GTA2; GTH2
Database LinkNP_000837
Entrez Gene 2939 Human
Entrez Gene 709037 Monkey
FunctionCytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq]
Related Pathway Glutathione metabolismMetabolism of xenobiotics by cytochrome P450Drug metabolism - cytochrome P450

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug of whole cell lysate). A:Hep G2. 12% SDS PAGE. TA308025 diluted at 1:3000
IHC Image
Immunohistochemical analysis of paraffin-embedded Stomach, using GSTA2(TA308025) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of methanol-fixed Hep G2, using GSTA2(TA308025) antibody at 1:500 dilution.

 

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