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Anti-GSS TRUEMAB Antibody Clone OTI2G3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA501935 GSS (Glutathione Synthetase) mouse monoclonal antibody, clone OTI2G3 (formerly 2G3) 100ul 379
In Stock
LC424876 GSS HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501935 Carrier-free (BSA/glycerol-free) GSS mouse monoclonal antibody, clone OTI2G3 (formerly 2G3) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human GSS (NP_000169) produced in HEK293T cell.
Clone NameClone OTI2G3 IsotypeIgG1
Species ReactivityHuman , Dog , Rat Concentration0.6 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:500~2000, FLOW 1:100
Predicted MW Explanation 52.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens glutathione synthetase (GSS)
Alternative NameGSHS; HEL-S-64p; HEL-S-88n
Database LinkNP_000169
Entrez Gene 2937 Human
Entrez Gene 25458 Rat
Entrez Gene 442962 Dog
FunctionGlutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq].
Related PathwayDruggable Genome Glutathione metabolismMetabolic pathways

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GSS (RC203174, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GSS.

WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-GSS monoclonal antibody.

WB Image
Western blot analysis of extracts (10ug) from a mouse cell line and 3 different mouse tissues by using anti-GSS monoclonal antibody.(1:200)

FC Image
HEK293T cells transfected with either RC203174 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-GSS antibody(TA501935), and then analyzed by flow cytometry.


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