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Anti-GSR Antibody EPR7238


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against Glutathione Reductase (GSR)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424558) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Glutathione Reductase was used as an immunogen.
Clone NameEPR7238 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100
Predicted MW Explanation 56 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens glutathione reductase (GSR), transcript variant 1
Alternative NameHEL-75
Database LinkNP_000628
Entrez Gene 2936 Human
Entrez Gene 14782 Mouse
Entrez Gene 116686 Rat
FunctionGlutathione Reductase is a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. Glutathione Reductase is a central enzyme of cellular antioxidant defense and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in Glutathione Reductase result in hereditary glutathione reductase deficiency (1).
Related PathwayDruggable Genome Glutathione metabolism

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-Glutathione Reductase antibody [EPR7238]; All lanes : Anti-Glutathione Reductase antibody [EPR7238] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : A549 cell lysate.Lane 4 : Caco-2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 56 kDa.
Flow Cytometry - Anti-Glutathione Reductase antibody [EPR7238]; TA310554, at a 1/10 dilution, staining Glutathione Reductase in permeabilized HeLa cells by Flow Cytometry (red). Analysis with a rabbit IgG (negative control) is shown in green.


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