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Anti-GSR Antibody EPR7238
|A synthetic peptide corresponding to residues in human Glutathione Reductase was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens glutathione reductase (GSR), transcript variant 1|
Entrez Gene 2936 Human
Entrez Gene 14782 Mouse
Entrez Gene 116686 Rat
|Glutathione Reductase is a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. Glutathione Reductase is a central enzyme of cellular antioxidant defense and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in Glutathione Reductase result in hereditary glutathione reductase deficiency (1).|
|Druggable Genome Glutathione metabolism|
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Western blot - Anti-Glutathione Reductase antibody [EPR7238]; All lanes : Anti-Glutathione Reductase antibody [EPR7238] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : A549 cell lysate.Lane 4 : Caco-2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 56 kDa.
Flow Cytometry - Anti-Glutathione Reductase antibody [EPR7238]; TA310554, at a 1/10 dilution, staining Glutathione Reductase in permeabilized HeLa cells by Flow Cytometry (red). Analysis with a rabbit IgG (negative control) is shown in green.